Regis Achiral Column

Celeris™ Ethyl Pyridine
Celeris™ Arginine
Achiral Column.png

Ethyl pyridine phases are the workhorse phases for preparative and process scale SFC purifications. Celeris 2EP (2-ethyl pyridine) and 4EP (4-ethyl pyridine) media is designed to be highly reproducible based on tight product specifications and low metal content. Celeris 2EP is especially well-suited for separation of acidic compounds and exhibits broad selectivity towards a variety of other compound types. The Celeris 4EP phase offers alternate selectivity to the 2EP phase. Celeris 2EP and 4EP SFC columns deliver high performance separations comparable to competing ethyl pyridine phases at a much lower price.

Celeris™ Amino

Celeris™ Arginine columns are packed with a silica surface modified with the amino acid arginine and exhibit both acidic and basic functionality. The phase has a strong affinity to hydrophilic compounds and offers a mixed-mode type of selectivity compared to other SFC phases.

The Celeris family of achiral stationary phases has been specifically designed for Supercritical Fluid Chromatography (SFC) separations, delivering high capacity, broad selectivity, excellent peak shapes, and reproducible performance over long column lifetimes. SFC provides a greener alternative to High-Performance Liquid Chromatography (HPLC) separation of complex samples containing a range of different functional groups and polarities. SFC provides better resolution, faster separation, and higher sample throughput compared to HPLC. However, these achiral columns are optimized to work with both the high pressures of SFC and HPLC systems.

Celeris™ PEI

Celeris™ Amino columns are packed with a traditional propyl-amine phase bonded to 100Å silica. This offers a high degree of polar selectivity over traditional silica or Ethyl Pyridine phases, allowing a high degree of retention for polar amine compounds.

The Celeris family of achiral stationary phases has been specifically designed for Supercritical Fluid Chromatography (SFC) separations, delivering high capacity, broad selectivity, excellent peak shapes, and reproducible performance over long column lifetimes. SFC provides a greener alternative to High-Performance Liquid Chromatography (HPLC) separation of complex samples containing a range of different functional groups and polarities. SFC provides better resolution, faster separation, and higher sample throughput compared to HPLC. However, these achiral columns are optimized to work with both the high pressures of SFC and HPLC systems.

Celeris™ Silica

Celeris™ polyethylenimine (PEI) columns are packed with a modified polymer, which includes several tertiary amine groups in the skeleton of the phase. The phase has nearly three times more amino groups than traditional Amino phases. This provides unique selectivity and allows for faster elution to give high quality separations in shorter times.

The Celeris family of achiral stationary phases has been specifically designed forSupercritical Fluid Chromatography (SFC) separations, delivering high capacity, broad selectivity, excellent peak shapes, and reproducible performance over long column lifetimes. SFC provides a greener alternative to High-Performance Liquid Chromatography (HPLC) separation of complex samples containing a range of different functional groups and polarities. SFC provides better resolution, faster separation, and higher sample throughput compared to HPLC. However, these achiral columns are optimized to work with both the high pressures of SFC and HPLC systems.

Celeris™ Diol

Celeris™ Silica columns are packed with ultra-pure, metal-free silica that offers great polar selectivity.

The Celeris family of achiral stationary phases has been specifically designed for Supercritical Fluid Chromatography (SFC) separations, delivering high capacity, broad selectivity, excellent peak shapes, and reproducible performance over long column lifetimes. SFC provides a greener alternative to High-Performance Liquid Chromatography (HPLC) separation of complex samples containing a range of different functional groups and polarities. SFC provides better resolution, faster separation, and higher sample throughput compared to HPLC. However, these achiral columns are optimized to work with both the high pressures of SFC and HPLC systems.

Celeris high performance phases provide rapid separation and recovery of purified components at a lower price than competitor offerings, enabling the use of larger column sizes to reduce the number of purification cycles required to achieve purity of the batch.

The Celeris™ Diol phase is a traditional diol phase bonded to 100Å silica and offers alternate selectivity to silica columns, often with increased retention. The separation mechanism of the diol phase is hydrogen bonding interactions between diol groups and polar compounds.

The Celeris family of achiral stationary phases has been specifically designed forSupercritical Fluid Chromatography (SFC) separations, delivering high capacity, broad selectivity, excellent peak shapes, and reproducible performance over long column lifetimes. SFC provides a greener alternative to High-Performance Liquid Chromatography (HPLC) separation of complex samples containing a range of different functional groups and polarities. SFC provides better resolution, faster separation, and higher sample throughput compared to HPLC. However, these achiral columns are optimized to work with both the high pressures of SFC and HPLC systems.

Regis Blue Baner Logo.png